St. Jerome gives the date of 94 B.C. for the birth of Lucretius and says that he committed suicide at the age of 44. Jerome also says Luretius wrote the work between bouts of madness. This is considered gossip rather than fact, but we have very little factual information. His patron was Gaius Memmius, who is addressed in De rerum natura, and was married to Fausta, the daughter of the Roman dictator Sulla. Lucretius may have come from the clan of the Lucretii and he may have been married to a Lucilla.
For more on Lucretius, see Lucretius and Epicureanism.